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El-Serag Digestive Diseases and Sciences .2024

Limitations of This Comparison Several structural limitations constrain everything above, and honest readers should keep them in view: Species and model gap

Toxicol., 46: 277-285

Moreover, the affinity of Acs1 for acetate is reported to be several times greater than that of the constitutively expressed Acs2 isoform, suggesting that Acs1 is primarily responsible for acetyl-CoA synthesis during growth on non-fermentable carbon sources such as ethanol 26